Modifications



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Base type RNA Source Phylogenetic Occurrence



























# Symbol Common Name
1 m1A 1-methyladenosine
2 m2A 2-methyladenosine
3 m6A N6-methyladenosine
4 Am 2'-O-methyladenosine
5 ms2m6A 2-methylthio-N6-methyladenosine
6 i6A N6-isopentenyladenosine
7 ms2i6A 2-methylthio-N6-isopentenyladenosine
8 io6A N6-(cis-hydroxyisopentenyl)adenosine
9 ms2io6A 2-methylthio-N6-(cis-hydroxyisopentenyl) adenosine
10 g6A N6-glycinylcarbamoyladenosine
11 t6A N6-threonylcarbamoyladenosine
12 ms2t6A 2-methylthio-N6-threonyl carbamoyladenosine
13 m6t6A N6-methyl-N6-threonylcarbamoyladenosine
14 hn6A N6-hydroxynorvalylcarbamoyladenosine
15 ms2hn6A 2-methylthio-N6-hydroxynorvalyl carbamoyladenosine
16 Ar(p) 2'-O-ribosyladenosine (phosphate)
17 I inosine
18 m1I 1-methylinosine
19 m1Im 1,2'-O-dimethylinosine
20 m3C 3-methylcytidine
21 m5C 5-methylcytidine
22 Cm 2'-O-methylcytidine
23 s2C 2-thiocytidine
24 ac4C N4-acetylcytidine
25 f5C 5-formylcytidine
26 m5Cm 5,2'-O-dimethylcytidine
27 ac4Cm N4-acetyl-2'-O-methylcytidine
28 k2C lysidine
29 m1G 1-methylguanosine
30 m2G N2-methylguanosine
31 m7G 7-methylguanosine
32 Gm 2'-O-methylguanosine
33 m22G N2,N2-dimethylguanosine
34 m2Gm N2,2'-O-dimethylguanosine
35 m22Gm N2,N2,2'-O-trimethylguanosine
36 Gr(p) 2'-O-ribosylguanosine (phosphate)
37 yW wybutosine
38 o2yW peroxywybutosine
39 OHyW hydroxywybutosine
40 OHyW* undermodified hydroxywybutosine
41 imG wyosine
42 mimG methylwyosine
43 Q queuosine
44 oQ epoxyqueuosine
45 galQ galactosyl-queuosine
46 manQ mannosyl-queuosine
47 preQ0 7-cyano-7-deazaguanosine
48 preQ1 7-aminomethyl-7-deazaguanosine
49 G+ archaeosine
50 Y pseudouridine
51 D dihydrouridine
52 m5U 5-methyluridine
53 Um 2'-O-methyluridine
54 m5Um 5,2'-O-dimethyluridine
55 m1Y 1-methylpseudouridine
56 Ym 2'-O-methylpseudouridine
57 s2U 2-thiouridine
58 s4U 4-thiouridine
59 m5s2U 5-methyl-2-thiouridine
60 s2Um 2-thio-2'-O-methyluridine
61 acp3U 3-(3-amino-3-carboxypropyl)uridine
62 ho5U 5-hydroxyuridine
63 mo5U 5-methoxyuridine
64 cmo5U uridine 5-oxyacetic acid
65 mcmo5U uridine 5-oxyacetic acid methyl ester
66 chm5U 5-(carboxyhydroxymethyl)uridine
67 mchm5U 5-(carboxyhydroxymethyl)uridine methyl ester
68 mcm5U 5-methoxycarbonylmethyluridine
69 mcm5Um 5-methoxycarbonylmethyl-2'-O-methyluridine
70 mcm5s2U 5-methoxycarbonylmethyl-2-thiouridine
71 nm5s2U 5-aminomethyl-2-thiouridine
72 mnm5U 5-methylaminomethyluridine
73 mnm5s2U 5-methylaminomethyl-2-thiouridine
74 mnm5se2U 5-methylaminomethyl-2-selenouridine
75 ncm5U 5-carbamoylmethyluridine
76 ncm5Um 5-carbamoylmethyl-2'-O-methyluridine
77 cmnm5U 5-carboxymethylaminomethyluridine
78 cmnm5Um 5-carboxymethylaminomethyl- 2'-O-methyluridine
79 cmnm5s2U 5-carboxymethylaminomethyl-2-thiouridine
80 m62A N6,N6-dimethyladenosine
81 Im 2'-O-methylinosine
82 m4C N4-methylcytidine
83 m4Cm N4,2'-O-dimethylcytidine
84 hm5C 5-hydroxymethylcytidine
85 m3U 3-methyluridine
86 m1acp3Y 1-methyl-3-(3-amino-3-carboxypropyl) pseudouridine
87 cm5U 5-carboxymethyluridine
88 m6Am N6,2'-O-dimethyladenosine
89 m62Am N6,N6,2'-O-trimethyladenosine
90 m2,7G N2,7-dimethylguanosine
91 m2,2,7G N2,N2,7-trimethylguanosine
92 m3Um 3,2'-O-dimethyluridine
93 m5D 5-methyldihydrouridine
94 m3Y 3-methylpseudouridine
95 f5Cm 5-formyl-2'-O-methylcytidine
96 m1Gm 1,2'-O-dimethylguanosine
97 m1Am 1,2'-O-dimethyladenosine
98 tm5U 5-taurinomethyluridine
99 tm5s2U 5-taurinomethyl-2-thiouridine
100 imG-14 4-demethylwyosine
101 imG2 isowyosine
102 ac6A N6-acetyladenosine
103 inm5U 5-(isopentenylaminomethyl)uridine
104 inm5s2U 5-(isopentenylaminomethyl)- 2-thiouridine
105 inm5Um 5-(isopentenylaminomethyl)- 2'-O-methyluridine
106 m2,7Gm N2,7,2'-O-trimethylguanosine
107 m42Cm N4,N4,2'-O-trimethylcytidine
108 C+ agmatidine
109 m8A 8-methyladenosine
110 gmnm5s2U geranylated 5-methylaminomethyl-2-thiouridine
111 gcmnm5s2U geranylated 5-carboxymethylaminomethyl-2-thiouridine
112 cnm5U 5-cyanomethyl-uridine