3-methyluridine
- Common name:
- 3-methyluridine
- Symbol:
- m3U
- CA index name:
- Uridine, 3-methyl-
- CA registry numbers:
- ribonucleoside 2140-69-4
- base 608-34-4
- elemental composition:
- C10H14N2O6
- nucleoside mass:
- 258.23

Source type | phylogenetic source | ||
---|---|---|---|
archaea | bacteria | eukarya | |
rRNA | 23S [1] | 16, 23S [2] | 18, 28S [4]25, 28S [5] |
Comment: In a recent examination of E. coli 23S rRNA, m3U was not detected [3]. |
Structure: [4]
Synthesis: [6]
Comment: Verification that the early report of m3U synthesis [5] was correct was made much later [7]. Although this nucleoside was reported present in both 18S and 28S rRNA from HeLa cells [4], later studies showed it to be confined to the 28S rRNA [5].
References:
- Noon, K.R., Bruenger, E. and McCloskey, J.A. (1998) J. Bacteriol., 180, 2883-2888.
- Johnson, J.D. and Horowitz, J. (1971) Biochim. Biophys. Acta, 247, 262-279.
- Kowalak, J.A., Pomerantz, S.C., Crain, P.F. and McCloskey, J.A. (1993) Nucleic Acids Res. 21, 4577-4585.
- Iwanami, Y. and Brown, G. (1968) Arch. Biochem. Biophys., 126, 8-15.
- Klagsbrun, M. (1973) J. Biol. Chem., 248, 2612-2620.
- Levene, P.A. and Tipson, R.S. (1934) J. Biol. Chem., 104, 385-393.
- Miles, H.T. (1956) Biochim. Biophys. Acta, 22, 247-253.