N4-methylcytidine

Common name:
N4-methylcytidine
Symbol:
m4C
CA index name:
Cytidine, N-methyl
CA registry numbers:
ribonucleoside 10578-79-7
base 6220-47-9
elemental composition:
C10H15N3O5
nucleoside mass:
257.25
rna-image
Source type phylogenetic source
archaea bacteria eukarya
rRNA 13S mt [1]

Structure: [1]


Synthesis: [2]


Comment: The base (m4Cyt) was previously reported in acid-treated HeLa rRNA, and was presumed to have originated from N4,2'-O-dimethylcytidine [3].


References:


  1. Dubin, D.T., Taylor, R.H. and Davenport, L.W. (1978) Nucleic Acids Res., 5, 4385-4397.
  2. Fox, J.J., Van Praag, D., Wempen, I., Doerr, I.L., Cheong, L., Knoll, J.E., Eidinoff, M.L., Bendich, A. and Brown, G.B. (1959) J. Am. Chem. Soc., 81, 178-187.
  3. Iwanami, Y. and Brown, G. (1968) Arch. Biochem. Biophys., 126, 8-15.