5-carbamoylmethyl-2'-O-methyluridine

Common name:
5-carbamoylmethyl-2'-O-methyluridine
Symbol:
ncm5Um
CA index name:
Uridine, 5-(2-amino-2-oxoethyl)-2'-O-methyl-
CA registry numbers:
ribonucleoside 60197-30-0
base not assigned
elemental composition:
C12H17N3O7
nucleoside mass:
315.28
rna-image
Source type phylogenetic source
archaea bacteria eukarya
tRNA +

Structure: [1]


Synthesis: [2], [3]


Comment: The first preparation of ncm5Um was by conversion of cm5Um which had been isolated from tRNA in the same study [2]. Conventional chemical synthesis of ncm5Um is reported in [3].


References:


  1. Gray, M.W. (1975) Can. J. Biochem., 53, 735-746.
  2. Gray, M.W. and Thomas, C. (1976) Biochemistry, 15, 3046-3051.
  3. Sochacka, E. and Malkiewicz, A. (1990) Nucleosides Nucleotides, 9, 793-802.