5-aminomethyl-2-thiouridine

Common name:
5-aminomethyl-2-thiouridine
Symbol:
nm5s2U
CA index name:
Uridine, 5-(aminomethyl)-2-thio-
CA registry numbers:
ribonucleoside 109666-14-0
base
elemental composition:
C10H15N3O5S
nucleoside mass:
289.31
rna-image
Source type phylogenetic source
archaea bacteria eukarya
tRNA +

Structure: [1]


Synthesis: None reported.


Comment: Observed as a component of unfractionated tRNA from E. coli mutants, as a biosynthetic precursor to mnm5s2U [1]; not rigorously characterized by conventional means. No chemical synthesis reported.


References:


  1. Hagervall, T.G., Edmonds, C.G., McCloskey, J.A. and Björk, G.R. (1987) J. Biol. Chem., 262, 8488-8495.