queuosine

Common name:
queuosine
Symbol:
Q
CA index name:
4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino- 5-[[(4,5-dihydroxy-2-cyclopenten-1-yl)amino]methyl]- 1,7-dihydro- 7-b-D-ribofuranosyl-, [1S-(1a,4b,5b>)]-
CA registry numbers:
ribonucleoside 57072-36-3
base 72496-59-4
elemental composition:
C17H23N5O7
nucleoside mass:
409.4
rna-image
Source type phylogenetic source
archaea bacteria eukarya
tRNA + +

Structure: [1]


Synthesis: [2]


Comment: Characterization of queuine, the base of queuosine, is reported in [3]. Biosynthesis of qeuosine has recently been reviewed [4].


References:


  1. Kasai, H., Ohashi, Z., Harada, F., Nishimura, S., Oppenheimer, N.J., Crain, P.F., Liehr, J.G., von Minden, D.L. and McCloskey, J.A. (1975) Biochemistry, 14, 4198-4208.
  2. Ohgi, T., Kondo, T. and Goto, T. (1977) Tetrahedron Lett., 4051-4054.
  3. Crain, P.F., Sethi, S.K., Katze, J.R. and McCloskey, J.A. (1980) J. Biol. Chem., 255, 8405-8407.
  4. Iwata-Reuyl, D. (2003) Bioorg. Chem., 31, 24-43.