wybutosine

Common name:
wybutosine
Symbol:
yW
CA index name:
3H-Imidazo[1,2-a]purine-7-butanoic acid, 4,9-dihydro- a-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-b-D-ribofuranosyl-, methyl ester, (S)-
CA registry numbers:
ribonucleoside 55196-46-8
base 35693-91-5
elemental composition:
C21H28N6O9
nucleoside mass:
508.49
rna-image
Source type phylogenetic source
archaea bacteria eukarya
tRNA +

Structure: [1], [2]


Synthesis: [2]


Comment: Nomenclature for the yW family of nucleosides is discussed in [3] and [4]. Errata for structure determination of yW [1] are reported in [2]. Alternate commonly used name is "Y nucleoside". Commonly used symbol for the corresponding base is Y. Structural characterization was made from the acid-liberated base. A Chemical Abstracts registry number was then assigned to the corresponding ribonucleoside.


References:


  1. Nakanishi, K., Furutachi, N., Funamizu, M., Grunberger, D. and Weinstein, I.B. (1970) J. Am. Chem. Soc., 92, 7617-7619.
  2. Funamizu, M., Terahara, A., Feinberg, A.M. and Nakanishi, K. (1971) J. Am. Chem. Soc., 93, 6706-6708.
  3. Blobstein, S.H., Grunberger, D., Weinstein, I.B. and Nakanishi, K. (1973) Biochemistry, 12, 188-193.
  4. Kasai, H., Goto, M., Ikeda, K., Zama, M., Mizuno, Y., Takemura, S., Matsuura, S., Sugimoto, T. and Goto, T. (1976) Biochemistry, 15, 898-904.