N2,N2,2'-O-trimethylguanosine

Common name:
N2,N2,2'-O-trimethylguanosine
Symbol:
m22Gm
CA index name:
Guanosine, N,N-dimethyl-2'-O-methyl-
CA registry numbers:
ribonucleoside 113886-73-0
base 24391-36-4
elemental composition:
C13H19N5O5
nucleoside mass:
325.32
rna-image
Source type phylogenetic source
archaea bacteria eukarya
tRNA +

Structure: [1]


Synthesis: [1]


Comment: Preliminary communication of structural characterization and chemical synthesis is given in [1]. Unknown nucleoside N-26 in Sulfolobus acidocaldarius tRNAiMet was postulated to be m22Gm in [2], without experimental evidence.


References:


  1. Edmonds, C.G., Crain, P.F., Hashizume, T., Gupta, R., Stetter, K.O. and McCloskey, J.A. (1987) J. Chem. Soc., Chem. Commun., 1987, 909-910.
  2. Kuchino, Y., Ihara, M., Yabusaki, Y. and Nishimura, S. (1982) Nature, 298, 684-685.