N6-methyladenosine

Common name:
N6-methyladenosine
Symbol:
m6A
CA index name:
Adenosine, N-methyl-
CA registry numbers:
ribonucleoside 1867-73-8
base 443-72-1
elemental composition:
C11H15N5O4
nucleoside mass:
281.27
rna-image
Source type phylogenetic source
archaea bacteria eukarya
tRNA + +
rRNA 16S [1] 16+23S [2]23S [3] [4]17S [5]18, 28S [6]
mRNA [7]
snRNA [8]

Structure: [4], [9]


Synthesis: [10]


Comment:


References:


  1. Noon, K.R., Bruenger, E. and McCloskey, J.A. (1998) J. Bacteriol., 180, 2883-2888.
  2. Starr, J.L. and Fefferman, R. (1964) J. Biol. Chem., 239, 3457-3461.
  3. Hayashi, Y., Osawa, S. and Miura, K. (1966) Biochim. Biophys. Acta, 129, 519-531.
  4. Littlefield, J.W. and Dunn, D.B. (1958) Nature, 181, 254-255.
  5. Cecchini, J.P. and Miassod, R. (1979) Eur. J. Biochem., 98, 203-214.
  6. Iwanami, Y. and Brown, G. (1968) Arch. Biochem. Biophys., 126, 8-15.
  7. Desrosiers, R., Friderici, K. and Rottman, F. (1974) Proc. Natl. Acad. Sci. USA, 71, 3971-3975.
  8. Reddy, R., Ro-Choi, T.S., Henning, D., Shibata, H., Choi, Y.C. and Busch, H. (1972) J. Biol. Chem., 247, 7245-7250.
  9. Adler, M., Weissmann, B. and Gutman, A.B. (1958) J. Biol. Chem., 230, 717-723.
  10. Johnson, J.A., Thomas, H.J. and Schaeffer, H.J. (1958) J. Am. Chem. Soc., 80, 699-702.