inosine

Common name:
inosine
Symbol:
I
CA index name:
Inosine
CA registry numbers:
ribonucleoside 58-63-9
base 68-94-0
elemental composition:
C10H12N4O5
nucleoside mass:
268.23
rna-image
Source type phylogenetic source
archaea bacteria eukarya
tRNA + + +
mRNA [3]

Structure: [1]


Synthesis: [2]


Comment: The presence of I in mRNA had been implied earlier from discrepencies between genomic and cDNA sequences, but [3] provides the first direct evidence for its occurrence.


References:


  1. Hall, R.H. (1963) Biochem. Biophys. Res. Commun., 13, 394-398.
  2. Levene, P.A. and Tipson, R.S. (1935) J. Biol. Chem., 111, 313-323.
  3. Morse, D.P. and Bass, B.L. (1997) Biochemistry, 36, 8429-8434.